Pat the chicken drumsticks dry with paper towels.
In a small bowl, mix together salt, black pepper, garlic powder, smoked paprika, onion powder, and cayenne pepper.
Rub the spice mixture evenly over all the chicken drumsticks.
In a separate bowl, whisk together barbecue sauce, honey, soy sauce, olive oil, apple cider vinegar, and minced garlic until well combined.
Place the seasoned chicken drumsticks into the crock pot in a single layer.
Pour the sauce mixture over the chicken drumsticks, ensuring they are well coated.
Cover the crock pot with the lid and cook on low heat for 4 hours and 30 minutes, or until the chicken is cooked through and tender.
Once cooked, carefully remove the chicken drumsticks from the crock pot and place them on a serving platter.
If desired, spoon some of the sauce from the crock pot over the drumsticks before serving.